MCP3426, MCP3427, & MCP3428 16-Bit ADCs Microchip Technology MCP3426, MCP3427, and MCP3428 16-Bit ADCs are low noise, high accuracy, Delta-Sigma (ΔΣ) Analog-to-Digital Converters with an I2C interface and onboard reference. The MCP3426 and MCP3427 devices have two differential input channels and the MCP3428 has four differential input channels. All electrical properties of these three devices are the same except for the differences in the number of input channels and I2C address bit selection options.